CSG Chicago Cubs

Houston Astros vs. Chicago Cubs prediction, pick for MLB on Friday 5/22/26

DraftKings

The Astros and Cubs play the first game of their three-game series on Friday, May 22. Chicago is a -144 moneyline favorite, while Houston is +119...

By Brendan O'Sullivan

Published: May 21, 2026, 10:30 pm Added: May 21, 2026, 11:46 pm
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